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Representative publications in 2014

September 15, 2023

1. Nie L, Chen X*. Structural and functional photoacoustic molecular tomography aided by emerging contrast agents. Chem Soc Rev. 2014 Sep 22;43(20):7132-70. doi: 10.1039/c4cs00086b.IF= 30.425

2. Lin LS, Cong ZX, Cao JB, Ke KM, Peng QL, Gao J, Yang HH*, Liu G*, Chen X. Multifunctional Fe₃O₄@polydopamine core-shell nanocomposites for intracellular mRNA detection and imaging-guided photothermal therapy. ACS Nano. 2014 Apr 22;8(4):3876-83. doi: 10.1021/nn500722y. Epub 2014 Mar 26. IF= 12.033

3. Sun X, Huang X, Yan X, Wang Y, Guo J, Jacobson O, Liu D, Szajek LP, Zhu W, Niu G, Kiesewetter DO, Sun S, Chen X.Chelator-Free Cu-64-Integrated Gold Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy. ACS Nano. 2014 Aug 26;8(8):8438-46. IF=12.033

4. Nie L, Huang P, Li W, Yan X, Jin A, Wang Z, Tang Y, Wang S, Zhang X, Niu G, Chen X. Early-StageImaging of Nanocarrier-Enhanced Chemotherapy Response in Living Subjects by Scalable Photoacoustic Microscopy. ACS Nano. 2014 Dec 23;8(12):12141-50. doi: 10.1021/nn505989e. Epub 2014 Nov 21. IF=12.033

5. Zhang L, Gao S, Zhang F,Yang K, Ma Q, Zhu L.ActivatableHyaluronic Acid Nanoparticle as a Theranostic Agent for Optical/Photoacoustic Image-Guided Photothermal Therapy. ACS Nano. 2014 Dec 23;8(12):12250-8. doi: 10.1021/nn506130t. Epub 2014 Nov 19. IF=12.033

6. Wang Z, Wang Z, Liu D, Yan X, Wang F, Niu G, Yang M, Chen X. Biomimetic RNA-Silencing Nanocomplexes: Overcoming Multidrug Resistance in Cancer Cells. Angew Chem Int Ed Engl. 2014 Feb 10;53(7):1997-2001. doi: 10.1002/anie.201309985. Epub 2014 Jan 20. IF= 11.336

7. Wang Z, Liu G*, Zheng H, Chen X*. Rigid nanoparticle-based delivery of anti-cancer siRNA: challenges and opportunities. Biotechnol Adv. 2014 Jul-Aug;32(4):831-43. doi: 10.1016/j.biotechadv.2013.08.020. Epub 2013 Sep 5. IF= 8.905

8. Guo M, Mao H, Li Y, Zhu A, He H, Yang H, Wang Y, Tian X, Ge C, Peng Q, Wang X, Yang X, Chen X, Liu G*, Chen H*. Dual imaging-guided photothermal/photodynamic therapy using micelles.Biomaterials. 2014.May ;35(16):4656-66.doi: 10.1016/j.biomaterials.2014.02.018. Epub 2014 Mar 6. IF= 8.312

9. Cheng L, Gong H, Zhu W, Liu J, Wang X, Liu G*, Liu Z*.PEGylated Prussian blue nanocubes as a theranostic agent for simultaneous cancer imaging and photothermal therapy.Biomaterials. 2014 Dec;35(37):9844-52. doi: 10.1016/j.biomaterials.2014.09.004. Epub 2014 Sep 16. IF=8.312

10. Xu L, He D, Li Z, Zheng J, Yang L, Yu M, Yu H, Chen Y, Que Y, Shih JW, Liu G, Zhang J, Zhao Q, Cheng T*, Xia N.Protection against lethal Enterovirus 71 challenge in mice by a recombinant vaccine candidate containing a broadly cross-neutralizing epitope within the VP2 EF loop. Theranostics. 2014 Feb 18;4(5):498-513. doi: 10.7150/thno.7457. eCollection 2014. IF= 7.827

11. Hu J, Zhu X, Li H, Zhao Z, Chi X, Huang G, Huang D, Liu G, Wang X, Gao J*. Theranostic Au cubic nano-aggregates as potential photoacoustic contrast and photothermal therapeutic agents. Theranostics. 2014 Feb 25;4(5):534-45. doi: 10.7150/thno.8188. eCollection 2014. IF= 7.827

12. Liming Nie,†, Shouju Wang,†, Xiaoyong Wang, Pengfei Rong, Ying Ma, Gang Liu, Peng Huang, Guangming Lu andXiaoyuan Chen,* In Vivo Volumetric Photoacoustic Molecular Angiography and Therapeutic Monitoring with Targeted Plasmonic Nanostars. Small. 2014 Apr 24;10(8):1585-93, 1441. doi: 10.1002/smll. IF=7.514

13. Zhao X*, Drlica K. Reactive oxygen species and the bacterial response to lethal stress. Curr Opin Microbiol. 2014 Oct;21C:1-6. doi: 10.1016/j.mib.2014.06.008. Epub 2014 Jul 30. IF= 7.216

14. Yuan X, Liu Y, Bai C, Luo Y, Wang R, Wang R, Cai Y, Zhao X*. Mycoplasma pneumoniae infection is associated with subacute cough. Eur Respir J. 2014 Apr;43(4):1178-81. doi: 10.1183/09031936.00067213. IF= 7.125

15. Huang SJ, Liu XH, Zhang J, Ng MH*. Protective immunity against HEV. Curr Opin Virol. 2014 Apr;5:1-6. doi: 10.1016/j.coviro. IF= 7.125

16. Li L, Hong Y, Luan G, Mosel M, Malik M, Drlica K, Zhao X*. Ribosomal elongation factor 4 promotes cell death associated with lethal stress. MBio. 2014 Dec 9;5(6). pii: e01708-14. doi: 10.1128/mBio.01708-14.if=6.875  

17. Liming Nie, Mei Chen, Xiaolian Sun, Pengfei Rong, Nanfeng Zheng * and Xiaoyuan Chen *. Palladium nanosheets as highly stable and effective contrast agents for in vivo photoacoustic molecular imaging. Nanoscale, 2014, 6, 1271-1276 IF= 6.739

18. Liu J, Wang L, Cao J, Huang Y, Lin Y, Wu X, Wang Z, Zhang F, Xu X*, Liu G*. Functional investigations on embryonic stem cells Labeled with clinically translatable iron oxide Nanoparticles. Nanoscale. 2014 Aug 7;6(15):9025-33. doi: 10.1039/c4nr01004c. IF=6.739

19. Xu Y, Liu Y, Wu Y, Xia X, Liao Y, Li Q. Fluorescent Probe-Based Lateral Flow Assay for

Multiplex Nucleic Acid Detection. Anal Chem. 2014 Jun 17;86(12):5611-4. doi: 10.1021/ac5010458. Epub 2014 Jun 6. IF=5.825

20. Guo J,†, Guo N,†, Lang L, Kiesewetter DO, Xie Q, Li Q, Eden HS, Niu G*, Chen X*. 18F-Alfatide II and 18F-FDG Dual-Tracer Dynamic PET for Parametric, Early Prediction of Tumor Response to Therapy. J Nucl Med,  2014Jan 1; 55(1):154-160.IF= 5.563

21. Zhu L, Ma Y, Kiesewetter DO, Wang Y, Lang L, Lee S, Niu G, Chen X. Rational Design of Matrix Metalloproteinase-13 Activatable Probes for Enhanced Specificity. ACS Chem Biol. 2014 Feb 21;9(2):510-6. doi: 10.1021/cb400698s. Epub 2013 Dec 3.IF=5.356

22. Zhang J, Zhang XF, Zhou C, Wang ZZ, Huang SJ, Yao X, Liang ZL, Wu T, Li JX, Yan Q, Yang CL, Jiang HM, Huang HJ, Xian YL, Shih JW, Ng MH, Li YM, Wang JZ*, Zhu FC, Xia NS*. Protection against hepatitis E virus infection by naturally acquired and vaccine-induced immunity. Clin Microbiol Infect. 2014 Jun;20(6):O397-405. doi: 10.1111/1469-0691.12419. Epub 2013 Nov 18. IF=5.197

23. Wang L, Wang X, Bhirde A, Cao J, Zeng Y, Huang X, Sun Y, Liu G*, Chen X*. Carbon-dot-based two-photon visible nanocarriers for safe and highly efficient delivery of siRNA and DNA.Adv Healthc Mater. 2014 Aug;3(8):1203-9. doi: 10.1002/adhm.201300611. Epub 2014 Apr 2. IF=4.88

24. Zhao Z, Yu Q, Mou T, Liu C, Yang W, Fang W, Peng C, Lu J, Liu Y, Zhang X*. Highly Efficient One-Pot Labeling of New Phosphonium Cations with Fluorine-18 as Potential PET Agents for Myocardial Perfusion Imaging. Mol Pharm. 2014, 11 (11), pp 3823–3831. IF= 4.787

25. Yue X, Wang Z, Zhu L, Wang Y, Qian C, Ma Y, Kiesewetter DO*, Niu G, Chen X*. Novel 19F activatable probe for the detection of matrix metalloprotease-2 activity by MRI/MRS. Mol Pharm. 2014 Nov 3;11(11):4208-17. doi: 10.1021/mp500443x. Epub 2014 Oct 13. IF= 4.787

26. Hu S, Li G, Li H, Liu X, Niu J, Quan S,Wang F, Wen H, Xu Y,Li Q*. Rapiddetection of isoniazidresistance in Mycobacteriumtuberculosisisolates by use of real-time-PCR-basedmeltingcurveanalysis. J Clin Microbiol. 2014 May;52(5):1644-52. doi: 10.1128/JCM.03395-13. Epub 2014 Mar 5. IF=4.232

27. Zhang S, Lin Y, Wang J, Wang P, Chen J, Xue M, He S, Zhou W, Xu F, Liu P, Chen P, Ge S*, Xia N et al. A convenient nucleic acid test on the basis of the capillary convective PCR for the on-site detection of Enterovirus 71.J Mol Diagn. 2014 Jul;16(4):452-8. doi: 10.1016/j.jmoldx.2014.04.002. Epub 2014 May 22.IF= 3.955

28. Xing R, Liu G*, Zhu J, Hou Y*, Chen X.Functional Magnetic Nanoparticles for Non-Viral Gene Deliveryand MR Imaging. Pharm Res. 2014 Jun;31(6):1377-89. doi: 10.1007/s11095-013-1205-2. Epub 2013 Sep 25.IF= 3.952

29. Li Z, Xu L, He D, Yang L, Liu C, Chen Y, Shih JW, Zhang J, Zhao Q, Cheng T, Xia N. In Vivo Time-Related Evaluation of a Therapeutic Neutralization Monoclonal Antibody against Lethal Enterovirus 71 Infection in a Mouse Model. PLoS One. 2014 Oct 3;9(10):e109391. doi: 10.1371/journal.pone.0109391. eCollection 2014. IF=3.534

30. Zhang S, Wang J, Yan Q, He S, Zhou W, Ge S*, Xia N. A one-step, triplex, real-time RT-PCR assay for the simultaneous detection of enterovirus 71, coxsackie A16 and pan-enterovirus in a single tube. PLoS One. 2014 Jul 16;9(7):e102724. doi: 10.1371/journal.pone.0102724. eCollection 2014. IF=3.534

31. Xu J, Wu F, Tian D, Wang J, Zheng Z, Xia N. Open reading frame 3 of genotype 1 hepatitis E virus inhibits nuclear factor-κappa B signaling induced by tumor necrosis factor-α in human A549 lung epithelial cells. PLoS One. 2014 Jun 24;9(6):e100787. doi: 10.1371/journal.pone.0100787. eCollection 2014. IF=3.534

32. Song N, Zhong X, Li Q. Real-timebidirectionalpyrophosphorolysis-activatedpolymerization for quantitativedetection of somaticmutations. PLoS One. 2014 Apr 25;9(4):e96420. doi: 10.1371/journal.pone.0096420. eCollection 2014. IF=3.534

33. Zhu FC, Huang SJ, Wu T, Zhang XF, Wang ZZ, Ai X, Yan Q, Yang CL, Cai JP, Jiang HM, Wang YJ, Ng MH, Zhang J*, Xia NS. Epidemiology of zoonotic hepatitis E: a community-based surveillance study in a rural population in China. PLoS One. 2014 Jan 31;9(1):e87154. doi: 10.1371/journal.pone.0087154. eCollection 2014. IF= 3.534

34. Li W*, Sun X, Wang Y, Niu G, Chen X, Qian Z, Nie L*. In vivo quantitative photoacoustic microscopy of gold nanostar kinetics in mouse organs. Biomed Opt Express. 2014 Jul 17;5(8):2679-85. doi: 10.1364/BOE.5.002679. eCollection 2014. IF=3.497

35. Wei M, Zhang X, Yu H, Tang ZM, Wang K, Li Z, Zheng Z, Li S, Zhang J, Xia N*, Zhao Q*. Bacteria expressed hepatitis E virus capsid proteins maintain virion-like epitopes. Vaccine. 2014 May 19;32(24):2859-65. doi: 10.1016/j.vaccine.2014.02.025. Epub 2014 Mar 22. IF= 3.485

36. Li T, Lin H, Zhang Y, Li M, Wang D, Che Y, Zhu Y, Li S, Zhang J, Ge S, Zhao Q, Xia N*. Improved characteristics and protective efficacy in an animal model of E. coli-derived recombinant double-layered rotavirus virus-like particles. Vaccine. 2014 Apr 7;32(17):1921-31. doi: 10.1016/j.vaccine.2014.01.093. Epub 2014 Feb 13. IF= 3.485

37. Zhang X, Wei M, Pan H, Lin Z, Wang K, Weng Z, Zhu Y, Xin L, Zhang J, Li S, Xia N, Zhao Q. Robust manufacturing and comprehensive characterization of recombinant hepatitis E virus-like particles in Hecolin(®).Vaccine. 2014 Jul 7;32(32):4039-50. doi: 10.1016/j.vaccine.2014.05.064. Epub 2014 Jun 2. IF= 3.485

38. Gui X, Li R, Zhang X, Shen C, Yu H, Guo X, Kang Y, Chen J, Chen H, Chen Y, Xia N. An important amino acid in nucleoprotein contributes to influenza A virus replication by interacting with polymerase PB2.Virology. 2014 Sep;464-465:11-20. doi: 10.1016/j.virol.2014.06.033. Epub 2014 Jul 18. IF= 3.278

39. You M, Xin L, Yang Y, Zhang X, Chen Y, Yu H, Li S, Zhang J, An Z, Luo W*, Xia N. Investigation of a special neutralizing epitope of HEVE2s. Protein Cell. 2014 Dec;5(12):950-3. doi: 10.1007/s13238-014-0115-3. IF=2.851

40. Liu C*, Guo Z, Zhang P, Song M, Zhao Z, Wu X, Zhang X*. Kit formulated asialoglycoprotein receptor targeting tracer based on copolymer for liver SPECT imaging. Nucl Med Biol. 2014 Aug;41(7):587-93. doi: 10.1016/j.nucmedbio.2014.04.005. Epub 2014 Apr 12. IF= 2.408

41. Chang Liu, Zhide Guo, Pu Zhang, Xianzhong Zhang. Copolymer based radiotracers for liver ASGP-R targeted SPECT imaging. Nucl Med Biol. Volume 41, Issue 7, Page 623, August 2014. IF=2.408

42. Yang L, He D, Tang M, Li Z, Liu C, Xu L, Chen Y, Du H, Zhao Q, Zhang J, Cheng T*, Xia N. Development of an enzyme-linked immunosorbent spot assay to measure serum-neutralizing antibodies against coxsackievirus B3. Clin Vaccine Immunol. 2014 Mar;21(3):312-20. doi: 10.1128/CVI.00359-13. Epub 2014 Jan 3. IF= 2.37

43. Cheng XD, Song LW, Fang LL, Yang L, Wu Y, Ge SX, Yuan Q*., Zhang J, Xia NS, Hao XK. Comparison of Three Luminescent Immunoassays for Hepatitis B Virus Surface Antigen Quantification during the Natural History of Chronic Hepatitis B Virus Infection.Clin Vaccine Immunol. 2014 Nov;21(11):1521-7. doi: 10.1128/CVI.00529-14. Epub 2014 Sep 10.IF= 2.37

44. Gui X, Ge P, Wang X, Yang K, Yu H, Zhao Q, Chen Y*, Xia N: Identification of a highly conserved and surface exposed B-cell epitope on the nucleoprotein of influenza A virus. J Med Virol. 2014 Jun;86(6):995-1002. doi: 10.1002/jmv.23812. Epub 2013 Oct 17. IF= 2.217

45. Su Y, Zhao B*, Guo F, Bin Z, Yang Y, Liu S, Han Y, Niu J, Ke X, Wang N, Geng X, Jin C, Dai Y, Lin Y. Interaction of benzo[a]pyrene with other risk factors in hepatocellular carcinoma: a case-control study in Xiamen, China. Ann Epidemiol. 2014 Feb;24(2):98-103. doi: 10.1016/j.annepidem.2013.10.019. Epub 2013 Nov 9.IF=2.145

46. Zhu Y, Zhang T, Zhao J, Weng Z, Yuan Q, Li S, Zhang J, Xia N*, Zhao Q*.Toward the development of monoclonal antibody-based assays to probe virion-like epitopes in hepatitis B vaccine antigen. Hum Vaccin Immunother. 2014 Apr;10(4):1013-23. Epub 2014 Feb 5. IF= 2.131

47. Zhao H, Lin ZJ, Huang SJ, Li J, Liu XH, Guo M, Zhang J, Xia NS,Pan HR*, Wu T*, Li CG*.   Correlation between ELISA and pseudovirion-based neutralisation assay for detecting antibodies against human papillomavirus acquired by natural infection or by vaccination. Hum Vaccin Immunother. 2014 Mar;10(3):740-6. Epub 2014 Jan 2.IF= 2.131

48. Hu YM, Huang SJ, Chu K, Wu T, Wang ZZ, Yang CL, Cai JP, Jiang HM, Wang YJ, Guo M, Liu XH, Huang HJ, Zhu FC, Zhang J*, Xia NS: Safety of an Escherichia coli-expressed bivalent human papillomavirus (types 16 and 18) L1 virus-like particle vaccine: An open-label phase I clinical trial. Hum Vaccin Immunother. 2014 Feb;10(2):469-75. doi: 10.4161/hv.26846. Epub 2013 Oct 25.IF=2.131

49. Zhao Q,Potter CS, Carragher B, Lander G, Sworen J, Towne V, Abraham D, Duncan P, Washabaugh MW, Sitrin RD*. Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy.  Hum Vaccin Immunother. 2014 Mar;10(3):734-9. Epub 2013 Dec 3. IF= 2.131

50. Chen L, Liu J, Wang W, Ye J, Wen L, Zhao Q, Zhu H, Cheng T*, Xia N. Development of a varicella-zoster virus neutralization assay using a glycoprotein K antibody enzyme-linked immunosorbent spot assay. J Virol Methods. 2014 May;200:10-4. doi: 10.1016/j.jviromet.2014.01.014. Epub 2014 Jan 31. IF= 1.883

51. Li T, Lin H, Yu L, Xue M, Ge S*, Zhao Q, Zhang J, Xia N. Development of an enzyme-linked immunospot assay for determination of rotavirus infectivity.J Virol Methods. 2014 Dec;209:7-14. doi: 10.1016/j.jviromet.2014.08.012. Epub 2014 Aug 27. IF= 1.883

52. Wu T, Zhang J, Xia N*. Rationally respond to post-vaccination adverse events. Sci China Life Sci. 2014 May;57(5):557-60. doi: 10.1007/s11427-014-4623-4. Epub 2014 Feb 13. IF= 1.512

53. Guo Z*, Zhang P, Song M, Wu X, Liu C, Zhao Z, Lu J, Zhang X*. Synthesis and preliminary evaluation of novel (99m)Tc-labeled folate derivative via click reaction for SPECT imaging. Appl Radiat Isot. 2014 Sep;91:24-30. doi: 10.1016/j.apradiso.2014.04.020. Epub 2014 May 14. IF= 1.056

54. Cheng L, Liu J, Gu X, Gong H, Shi X, Liu T, Wang C, Wang X, Liu G, Xing H, Bu W, Sun B, Liu Z*. PEGylated WS(2) nanosheets as a multifunctional theranostic agent for in vivo dual-modal CT/photoacoustic imaging guided photothermal therapy. Adv Mater. 2014 Mar 26;26(12):1886-93. doi: 10.1002/adma.201304497. Epub 2013 Dec 23. IF= 15.409

55. Huang P, Rong P, Jin A, Yan X, Zhang MG, Lin J, Hu H, Wang Z, Yue X, Li W, Niu G, Zeng W, Wang W, Zhou K, Chen X*. Dye-Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy. Adv Mater. 2014 Oct;26(37):6401-8. doi: 10.1002/adma.201400914. Epub 2014 Aug 14. IF=15.409

56. Zhen Z, Tang W, Chuang YJ, Todd T, Zhang W, Lin X, Niu G, Liu G, Wang L, Pan Z, Chen X, Xie J*. Tumor vasculature targeted photodynamic therapy for enhanced delivery of nanoparticles. ACS Nano. 2014 Jun 24;8(6):6004-13. doi: 10.1021/nn501134q. Epub 2014 May 12.\ IF= 12.033

57. Huang X, Zhang F, Wang Y, Sun X, Choi KY, Liu D, Choi JS, Shin TH, Cheon J, Niu G, Chen X*. Design Considerations of Iron-Based Nanoclusters for Noninvasive Tracking of Mesenchymal Stem Cell Homing. ACS Nano. 2014 May 27;8(5):4403-14. doi: 10.1021/nn4062726. Epub 2014 Apr 25. IF=12.033

58. Huang P, Rong P, Lin J, Li W, Yan X, Zhang MG, Nie L, Niu G, Lu J, Wang W, Chen X*. Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics. J Am Chem Soc. 2014 Jun 11;136(23):8307-13. doi: 10.1021/ja503115n. Epub 2014 Jun 2. IF= 11.444

59. Sun X, Huang X, Guo J, Zhu W, Ding Y, Niu G, Wang A, Kiesewetter DO, Wang ZL, Sun S, Chen X*. Self-illuminating Cu-64-Doped CdSe/ZnS Nanocrystals for in Vivo Tumor Imaging. J Am Chem Soc. 2014 Feb 5;136(5):1706-9. doi: 10.1021/ja410438n. Epub 2014 Jan 17. IF=11.444

60. He R, Wang YC, Wang X, Wang Z, Liu G, Zhou W, Wen L, Li Q, Wang X, Chen X, Zeng J*, Hou JG. Facile synthesis of pentacle gold-copper alloy nanocrystals and their plasmonic and catalytic properties. Nat Commun. 2014 Jul 7;5:4327. doi: 10.1038/ncomms5327. IF=10.742

61. Xuejiao Song, Hua Gong, Shengnan Yin, Liang Cheng, Chao Wang, Zhiwei Li, Yonggang Li, Xiaoyong Wang, Gang Liu andZhuang Liu,* Ultra-Small Iron Oxide Doped Polypyrrole Nanoparticles for In Vivo Multimodal Imaging Guided Photothermal Therapy. Advanced Functional Materials, Volume 24, Issue 9, pages 1194–1201, March 5, 2014. IF=10.439

62. Hu H, Huang P, Weiss OJ, Yan X, Yue X, Zhang MG, Tang Y, Nie L, Ma Y, Niu G, Wu K, Chen X*. PET and NIR optical imaging using self-illuminating (64)Cu-doped chelator-free gold nanoclusters. Biomaterials. 2014 Dec;35(37):9868-76. doi: 10.1016/j.biomaterials.2014.08.038. Epub 2014 Sep 15. IF=8.312

63. Chen J, Doyle TJ, Liu Y, Aggarwal R, Wang X, Shi Y, Ge SX, Huang H, Lin Q, Liu W, Cai Y, Koontz D, Fuhrman C, Golzarri MF, Liu Y, Hatabu H, Nishino M, Araki T, Dellaripa PF, Oddis CV, Rosas IO, Ascherman DP*. Biomarkers of Rheumatoid Arthritis-associated Interstitial Lung Disease. Arthritis Rheumatol. 2014 Oct 9. doi: 10.1002/art.38904 IF=7.871

64. Yang K †, Zhu L †, Nie L, Sun X, Cheng L, Wu C, Niu G, Chen X*, Liu Z*. Visualization of Protease Activity In Vivo Using an Activatable Photo-Acoustic Imaging Probe Based on CuS Nanoparticles. Theranostics 2014; 4(2):134-141. *co-first author. IF= 7.827

65. Rong P†, Yang K†, Srivastan A, Kiesewetter DO, Yue X, Wang F, Nie L, Bhirde A, Wang Z, Liu Z, Niu G*, Wang W*, Chen X*. Photosensitizer loaded nano-graphene for multimodality imaging guided tumor photodynamic therapy. Theranostics. 2014 Jan 15;4(3):229-39. doi: 10.7150/thno.8070. eCollection 2014. IF= 7.827

66. Wan Z†, Mao H†, Guo M, Li Y, Zhu A, Yang H, He H, Shen J, Zhou L, Jiang Z, Ge C, Chen X, Yang X, Liu G, Chen H*. Highly efficient hierarchical micelles integrating photothermal therapy and singlet oxygen-synergized chemotherapy for cancer eradication. Theranostics. 2014 Jan 29;4(4):399-411. doi: 10.7150/thno.8171. eCollection 2014. IF= 7.827

67. Choi KY, Silvestre OF, Huang X, Hida N, Liu G, Ho DN, Lee S, Lee SW, Hong JI, Chen X*. A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo. Nat Protoc. IF=8.362 2014 Aug;9(8):1900-15. doi: 10.1038/nprot.2014.128. Epub 2014 Jul 17. IF=7.782

68. Liu D*, Yang J, Wang HF, Wang Z, Huang X, Wang Z, Niu G, Hight Walker AR, Chen X. Glucose Oxidase-Catalyzed Growth of Gold Nanoparticles Enables Quantitative Detection of Attomolar Cancer Biomarkers. Anal Chem. 2014 Jun 17;86(12):5800-6. doi: 10.1021/ac500478g. Epub 2014 Jun 4. IF=5.825

69. Wen X, Huang X, Mok BW, Chen Y, Zheng M, Lau SY, Wang P, Song W, Jin DY, Yuen KY, Chen H*. NF90exertsantiviralactivity through regulation of PKRphosphorylation and stressgranules in infectedcells. J Immunol. 2014 Apr 15;192(8):3753-64. doi: 10.4049/jimmunol.1302813. Epub 2014 Mar 12. IF=5.362

70. Wang Z, Yue X, Wang Y, Qian C, Huang P, Lizak M, Niu G, Wang F, Rong P, Kiesewetter DO, Ma Y, Chen X*. A Symmetrical Fluorous Dendron-Cyanine Dye-Conjugated Bimodal Nanoprobe for Quantitative F-19 MRI and NIR Fluorescence Bioimaging. Adv Healthc Mater. 2014 Aug;3(8):1326-33. doi: 10.1002/adhm.201400088. Epub 2014 May 2. IF=4.88

71. Han Q, Chang C, Li L, Klenk C, Cheng J, Chen Y, Xia N, Shu Y, Chen Z, Gabriel G, Sun B*, Xu K*. Sumoylation of influenza A virus nucleoprotein is essential for intracellular trafficking and virus growth. J Virol. 2014 Aug;88(16):9379-90. doi: 10.1128/JVI.00509-14. IF=4.648

72. Li H, Zhuang Q, Wang Y, Zhang T, Zhao J, Zhang Y, Zhang J, Lin Y, Yuan Q, Xia N, Han J*. HBV life cycle is restricted in mouse hepatocytes expressing human NTCP. Cell Mol Immunol. 2014 Mar;11(2):175-83. doi: 10.1038/cmi.2013.66. Epub 2014 Feb 10. IF= 4.185

73. Hu W, Zhang H, Han Q, Li L, Chen Y, Xia N, Chen Z, Shu Y, Xu K*, Sun B*. A Vero-cell-adapted vaccine donor strain of influenza A virus generated by serial passages. Vaccine. 2014 Nov 18. pii: S0264-410X(14)01531-X. doi: 10.1016/j.vaccine.2014.11.007.IF=3.485

74. Ma Q, Chen B, Gao S, Ji T, Wen Q, Song Y, Zhu L, Xu Z, Liu Li *. 99mTc-3P4-RGD2 Scintimammography in the Assessment of Breast Lesions: Comparative Study with 99mTc-MIBI.PLoS One. 2014 Sep 24;9(9):e108349. doi: 10.1371/journal.pone.0108349. eCollection 2014. IF=3.73

75. Zhang H, An D, Liu W, Mao Q, Jin J, Xu L, Sun S, Jiang L, Li X, Shao J, Ma H, Huang X, Guo S, Chen H,Cheng T, Yang L, Su W, Kong W, Liang Z, Jiang C. Analysis of cross-reactiveneutralizingantibodies in humanHFMDserum with an EV71 pseudovirus-basedassay. PLoS One. 2014 Jun 25;9(6):e100545. doi: 10.1371/journal.pone.0100545. eCollection 2014. IF=3.73

76. Chen T, Leung RK, Zhou Z, Liu R, Zhang X, Zhang L*.Investigation of key interventions for shigellosis outbreak control in China. PLoS One. 2014 Apr 15;9(4):e95006. doi: 10.1371/journal.pone.0095006. eCollection 2014. IF=3.73

77. Yang W, Zhang X, Liu Y*. Asialoglycoprotein Receptor-Targeted Radiopharmaceuticals for Measurement of Liver Function. Current Medicinal Chemistry, Volume 21, Number 1, January 2014, pp. 4-23(20) IF= 3.715

78. Li C, Yuan M, Lu L, Lu T, Xia W, Pham VH, Vo AX, Nguyen MH, Abe K. The genetic diversity and evolutionary history of hepatitis C virus in Vietnam.Virology. 2014 Sep 2;468-470C:197-206. doi: 10.1016/j.virol.2014.07.026. IF=3.278

79. Guo J, Lang L, Hu S, Guo N, Zhu L, Sun Z, Ma Y, Kiesewetter DO, Niu G, Xie Q*, Chen X*.Comparison of Three Dimeric 18F-AlF-NOTA-RGD Tracers. Mol Imaging Biol. 2014 Apr;16(2):274-83. doi: 10.1007/s11307-013-0668-1. IF= 2.869

80. Wu, H.*, Chen, H., Pan, D., Ma, Y., Liang, S., Wan, Y., &Fang, Y. Imaging Integrin αvβ3 and NRP-1 Positive Gliomas with a Novel Fluorine-18 Labeled RGD-ATWLPPR Heterodimeric Peptide Probe. Molecular Imaging and Biology, 2014:16(6), 781-792. IF= 2.869

81. Wu HC, Tsai HW, Teng CF, Hsieh WC, Lin YJ, Wang LH, Yuan Q, Su IJ*. Ground-glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis. Hum Pathol. 2014 Jun;45(6):1294-301. doi: 10.1016/j.humpath.2013.10.039. Epub 2014 Feb 28. IF= 2.806

82. Wang P, Zeng Y, Liu T, Zhang C*, Yu PW, Hao YX, Luo HX, Liu G. Chloride intracellular channel 1 regulates colon cancer cell migration and invasion through ROS/ERK pathway. World J Gastroenterol. 2014 Feb 28;20(8):2071-8. doi: 10.3748/wjg.v20.i8.2071. IF= 2.433

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