教育经历

2009年9月至2014年7月：维多利亚老品牌vic119生命科学学院，生物化学与分子生物学专业，理学博士

2006年9月至2009年9月：维多利亚老品牌vic119生命科学学院，生物化学与分子生物学专业，理学硕士

2002年9月至2006年7月：维多利亚老品牌vic119生命科学学院生物技术专业，理学学士

工作经历

2024年5月至今：维多利亚老品牌vic119，教授

2019年8月至2024年4月：维多利亚老品牌vic119，高级工程师

2015年7月至2019年7月：维多利亚老品牌vic119，工程师

代表性论文（共同第一/通讯作者）

1.Pan H#, Yu S#, Zhuang H#, Yang H#, Jiang J, Yang H, Ren S, Luo G, Yu X, Chen S, Lin Y, Sheng R, Zhang S, Yuan Q, Huang C, Zhang T, Li T*, Ge S*, Zhang J and Xia N*. Orchestrated codelivery of peptide antigen and adjuvant to antigen-presenting cells by using an engineered chimeric peptide enhances antitumor T-cell immunity. Cancer Immunol Res. (2024)

2.Yu S#, Pan H#, Yang H, Zhuang H, Yang H, Yu X, Zhang S, Fang M, Li T*, Ge S*, Xia N*. A non-viral DNA delivery system consisting of multifunctional chimeric peptide fused with zinc-finger protein. iScience (2024)

3.Tang J#, Hao M#, Liu J, Chen Y, Wufuer G, Zhu J, Zhang X, Zheng T, Fang M, Zhang S, Li T*, Ge S, Zhang J and Xia N. Design of a recombinant asparaginyl ligase for site-specific modification using efficient recognition and nucleophile motifs. Commun Chem. (2024)

4.Huang Y#, Tang J#, Yu H#, Song Q, Hao M, Wang H, Liu J, Dong Y, Liang M, Zhuang S, Li C, Wang J, Liang C, Su Y, Li T*, Wu T, Ge S, Zhang J* and Xia N. Reconsideration of maternal serological testing for predicting congenital CMV infection. J Infect Dis. (2024)

5.Luo G, Zeng Y, Sheng R, Zhang Z, Li C, Yang H, Chen Y, Song F, Zhang S, Li T*, Ge S*, Zhang J, Xia N. Wa-VP4* as a candidate rotavirus vaccine induced homologous and heterologous virus neutralizing antibody responses in mice, pigs, and cynomolgus monkeys. Vaccine. (2024)

6.Li T#, Li F#, X. Guo#, Hong C#, Yu X#, Wu B, Lian S, Song L, Tang J, Wen S, Gao K, Hao M, Cheng W, Su Y, Zhang S, Huang S, Fang M, Wang Y, Ng M, Chen H, Luo W, Ge S*, Zhang J, Xia N* and Ji M*. Anti-Epstein-Barr Virus BNLF2b for Mass Screening for Nasopharyngeal Cancer. N Engl J Med. (2023)

7.Hao M, Tang J, Ge S, Li T*, Xia N. Bacterial-Artificial-Chromosome-Based Genome Editing Methods and the Applications in Herpesvirus Research. Microorganisms. (2023)

8.Wang Y#, Song F#, Wang S#*, Lan M#, Li T#, Guo H, Zhang Y, Ge S*, Zheng Z and Xia N. Nanoparticle-based multivalent human antibodies offer potent and broad neutralization against Omicron sublineages. Signal Transduct Target Ther. (2023)

9.Zeng Y#, Song F#, Luo G#, Yang H, Li C, Liu W, Li T*, Zhang S, Wang Y*, Huang C, Ge S*, Zhang J, Xia N. Generation and characterization of mouse monoclonal antibodies against the VP4 protein of group A human rotaviruses. Antiviral Res. (2022)

10.Luo G, Zeng Y, Yang H, Li Y, Yang L, Li C, Song F, Zhang S, Li T*, Ge S*, Zhang J and Xia N. Bivalent rotavirus VP4 * stimulates protective antibodies against common genotypes of human rotaviruses. iScience. (2022).

11.Li C#, Luo G#, Zeng Y, Song F, Yang H, Zhang S, Wang Y, Li T*, Ge S* and Xia N. Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production. Vaccines (Basel). (2022)

12.Yu S#, Yang H#, Li T#, Pan H, Ren S, Luo G, Jiang J, Yu L, Chen B, Zhang Y, Wang S, Tian R, Zhang T, Zhang S, Chen Y, Yuan Q*, Ge S*, Zhang J and Xia N. Efficient intracellular delivery of proteins by a multifunctional chimaeric peptide in vitro and in vivo. Nat Commun. (2021)

13.Huang Y#, Wang H#, Li T#, Li C#, Tang J, Yu H, Guo X, Song Q, Wei F, Wang J, Liang C, Zheng F, Li H, Li H, Wu H, Lu Z, Su Y, Wu T, Ge S*, Fu T*, Zhang J* and Xia N. Comparison of detection strategies for screening and confirming congenital cytomegalovirus infection in newborns in a highly seroprevalent population: a mother-child cohort study. The Lancet Regional Health - Western Pacific. 12:100182. (2021).

14.Guo X, Wang H, You R, Tang J, Wang J, Song Q, Huang Y, Zhang X, Zhang S, Li T*, Ge S*, Wu T, Zhang J and Xia N. Elimination of human cytomegalovirus DNA degradation in urine. J Med Virol. (2021)

15.Lou B#, Li T#, Zheng S#, Su Y#, Li Z#, Liu W, Yu F, Ge S*, Zou Q, Yuan Q, Lin S, Hong C, Yao X, Zhang X, Wu D, Zhou G, Hou W, Li T, Zhang Y, Zhang S, Fan J*, Zhang J*, Xia N and Y. Chen*. Serology characteristics of SARS-CoV-2 infection since exposure and post symptom onset. Eur Respir J. 56(2):2000763. (2020)

16.Zhu J*, Lu X, Li Y, Li T*, Yang L, Yang K, Ji L, Lu M, Li M. A Rotavirus Virus-Like Particle Confined Palladium Nanoreactor and Its Immobilization on Graphene Oxide for Catalysis. Catal Letters. (2020)

17.Zeng Y, Zhao B, Li T*, Zhang S, Wang Y, Xu H, Ge S* and Xia N. Molecular characterization of an uncommon multigene Reassortant G1P[4] rotavirus identified in China. Infect Genet Evol. (2020)

18.Yang H#, Ren S#, Yu S, Pan H, Li T*, Ge S, Zhang J and Xia N. Methods Favoring Homology-Directed Repair Choice in Response to CRISPR/Cas9 Induced-Double Strand Breaks. Int J Mol Sci. (2020)

承担科研项目

1.国家自然科学基金面上项目, 82171816, 轮状病毒VP4蛋白免疫保护机制研究, 2022-01至2025-12，54万元, 在研, 主持

2.国家自然科学基金面上项目,81974260，轮状病毒VP4蛋白交叉中和表位特征及其中和机制研究，2020-01至2023-12，55万元, 已结题, 主持

3.重点研发计划，2020YFC1316800，生物大分子胞内递送系统的研究，2020-01至2021-12，300万，已结题，参与

4.重点研发计划，2020YFC0843400，新型冠状病毒(2019-nCoV)抗体快速检测试剂盒的研制，2020-02至2020-04，30万，已结题，参与

5.传染病重大专项，2018ZX10732401-003-008，活动性结核与结核分支杆菌潜伏感染鉴别诊断试剂的研制，2018-01至2019-12，已结题，任务负责人

6.国家自然科学基金青年项目，轮状病毒VP8与VP5抗原区相互作用及解离机制的研究，81501741，2016-01至2019-12,21.6万，已结题，主持